Pulmonary Morphology Core

DirectorDerek Byers, MD, PhD
Contact: Darlene Stewart or Teresa Tolley
Phone: 314-362-3871
Email: pulmorphcore@dom.wustl.edu

Location: Clinical Science Research Building (CSRB) 9965

Website


Core summary

With over 25 years of experience, the Pulmonary Morphology Core provides histologic services for a variety of tissues from mice, humans, pigs, and other species.

Capabilities include:

  • Fixation of biologic samples
  • Embedding of fixed or frozen tissue in paraffin, plastic, or cryomatrix
  • Sectioning of embedded tissue specimens
  • Diverse histological staining methods

Core details

The Pulmonary Morphology Core provides investigators with extensive technical support in the fixation and processing of tissue specimens from all organ systems, sectioning of embedded samples, and multiple staining methods. Customer service is a priority, and the Core strives to make sure that tissue histology services are held to the highest standards.

Experience with many staining methods:

  • Hematoxylin & Eosin (H&E)
  • Periodic acid-Schiff (PAS)
  • Alcian Blue
  • Gomori’s Trichrome
  • Hart’s Elastin Stain
  • Von Kossa
  • Toluidine Blue
  • Bielschowsky
  • Geimsa
  • Methylene Green
  • Pentachrome
  • Perl’s Iron
  • Picosirius Red
  • PAS/Alcian Blue
  • Safranin O
  • Verhoff van-Giesen
  • Unique counterstains (Fast Green, tartrazine, others)

Other staining methods and custom services will be strongly considered.

Access

The Core is available to investigators at Washington University and other non-profit organizations. In 2014-2015, over 20 different labs in Pulmonary/Critical Care, Cardiothoracic Surgery, Pathology. Cardiology, Radiology, and Medical Oncology utilized the Pulmonary Morphology Core services. Priority is generally given to members of the Asthma and Allergic Diseases Cooperative Research Center and to the lung research community with established relationships to the Division of Pulmonary and Critical Care that support the daily operations of the Core.

Pricing

Please contact the Core for information.

Additional information

Affiliations

  • Division of Pulmonary and Critical Care Medicine, Department of Medicine, Washington University School of Medicine
  • Asthma and Allergic Diseases Cooperative Research Center
  • Pulmonary Airway Epithelial Cell Core