In September 2017, Mario Castro, MD, MPH received 2 new research grants. “Washington University K12 Program in T4 Implementation Research” from the NIH/NHLBI seeks to develop a K12 training program to train scholars to bridge research and practice in a variety of real-world settings with a focus on HLBS disorders. “Washington University’s Precision Biologic Interventions for Severe Exacerbation Prone Asthma (PRECISE) Clinical Center” from the NIH/NHLBI aims to study adolescent and adult patients with severe persistent exacerbation-prone asthma to evaluate which targeted biologic therapy, anti-IL4Ra, anti-IL5 or anti-lgE mAb, is most effective among patients with eosinophilic asthma, T2 asthma, or mucus-driven asthma.