Roger D. Yusen, M.D., M.P.H.

Assistant Professor of Medicine

CONTACT INFORMATION

Divisions of Pulmonary & Critical Care Medicine and General Medical Sciences
Washington University School of Medicine
Campus Box 8052
660 S. Euclid Ave.
St. Louis, MO 63110
Phone: (314) 454-8764
Fax: (314) 454-5571

EDUCATION/TRAINING

Undergraduate: University of Illinois, Champaign, IL, B.S. 1986

Medical School: University of Illinois, Chicago, IL, M.D. 1990

Graduate School: St. Louis University School of Public Health, St. Louis, MO, M.P.H. (Biostatistics Concentration) 2002

Internship: Duke University Medical Center, Durham, NC 1990-1991

Residency: Duke University Medical Center, Durham, NC 1991-1993

Fellowships: Pulmonary and Critical Care Medicine Washington University School of Medicine, St. Louis, MO 1993 - 1996

Technology Assessment Program
Division of General Medical Sciences
Washington University School of Medicine, St. Louis, MO 1996 - 1999

POSITIONS AND EMPLOYMENT

1995-present Staff physician, Barnes-Jewish Hospital

1999-present Assistant Professor of Medicine, Department of Medicine, Division of Pulmonary and Critical Care Medicine & General Medical Sciences, Washington University School of Medicine.

OTHER EXPERIENCE AND PROFESSIONAL MEMBERSHIPS

Editorial Service:
International Editorial Committee, Neumomadrid-Par

Peer review: American Journal of Respiratory and Critical Care Medicine
Anesthesiology
Annals of Internal Medicine
Annals of Thoracic Surgery
Archives of Internal Medicine
CHEST
European Respiratory Journal
Journal of the American Medical Association (JAMA)
Journal of Thoracic and Cardiovascular Surgery
Respiratory Care

National Committees:
National Institutes of Health (Heart, Lung, and Blood Institute), National Emphysema Therapy Trial ("NETT") (HR-97-02). Role: Subcommittee on medical management, working group on non-physiologic patient outcomes/health related quality of life, and subcommittee on cost-effectiveness, 1997.

National Institutes of Health (Heart, Lung, and Blood Institute), National Emphysema Therapy Trial ("NETT") (HR-97-02). Role: Advisory group for the NETT cost-effectiveness substudy, 1998 - 2003.

American College of Chest Physicians Committee on treatment guidelines for parapneumonic pleural effusions and empyema. Role: Collaborator and methodologist. Head of subcommittee on surgical treatment of parapneumonic pleural effusions and empyema, 1998-1999.

International Registry of Alpha 1-Antitrypsin Deficiency, United States Coordinating Center (Utah). Role: Head of quality of life assessment for the Advisory Committee, 1999-present.

North American Physician Advisory Panel to identify clinical relevant change in the Chronic Respiratory Questionnaire and the SF-36 health-related quality of life measures for patients with chronic obstructive pulmonary disease. Role: Member of Advisory Panel, 2000.

Prospective Investigation Of Pulmonary Embolism Diagnosis (PIOPED) II: Clinical Science Committee and Outcome committee, 2000-2004

DVT-FREE DVT Registry. Role: Steering committee member, 2001-2003

Thrombosis Council. Role: member, 2001-ongoing.

Spiration, Inc. Role: Scientific Advisory Board, 2001-ongoing.

American Thoracic Society Committee on Treatment of Pulmonary Embolism. Role: Committee member, 2001-ongoing.

EXtended CLinical prophylaxis of venous thromboembolism with enoxaparin in Acutely Ill Medical patients (EXCLAIM) randomized controlled trial. Role: Steering committee, 2002-ongoing.

American Thoracic Society / European Respiratory Society Guideline Committee. Standards for the Diagnosis and Treatment of Patients with COPD. Role: lung volume reduction surgery committee member. 2002-ongoing

NIH-NHLBI Working Group. Clinical Research in COPD: Needs and Opportunities. Role: working group member. 2002.

Clinical trial of a new device for lung volume reduction surgery. Role: Chair, Clinical Events Committee, 2002- current.

American Thoracic Society (ATS) Clinical Problems Assembly, Program Committee. Role: member. 2003-2004.

American Thoracic Society (ATS) Clinical Problems Assembly, Nominating Committee. Role: member. 2003-2004.

AWARDS AND HONORS

Undergraduate:
University of Illinois College of Liberal Arts and Sciences; Phi Beta Kappa, Alpha Lambda Delta Honor Society, Golden Key National Honor Society, Phi Kappa Phi Honor Society, Academic All-American, Harriet Aibinder Scholarship

Graduate:
University of Illinois College of Medicine; Alpha Omega Alpha Honor Society, Frances Pillsbury Scholarship, Ishiyaku EuroAmerica Annual Book Award

Postgraduate/Residency:
Duke University Medical Center; Assistant Chief Medical Resident (1992), Winner in Abstract Competition with Grand Rounds presentation (1993)

Postgraduate/Fellowship:
Washington University School of Medicine; Winner of Affiliates' Forum presentation American College of Chest Physician (1994), American College of Chest Physicians Young Investigator Award (1995), Norman P. Knowlton, Jr., M.D., Incentive for Excellence Award, Barnes- Jewish Hospital (1996, 1997)

Junior Faculty:
American College of Chest Physicians' Leadership Development in Pulmonary and Critical Care Medicine Program (1999), American College of Chest Physicians Young Investigator Award (2000).

PUBLICATIONS

RESEARCH SUPPORT

Ongoing Research Support - Government
1 K23 HL-04236-01 1/1/00 - 11/30/04
Source: National Institutes of Health; National Heart, Lung and Blood Institute
Type: Mentored Patient-Oriented Research Career Development Award (K23)
Title: Emphysema: Outcomes and Technology Assessment
Role: Principal Investigator

R01 HL6391-01A1 10/1/2000-9/31/2004
Source: National Institutes of Health; National Heart, Lung and Blood Institute
Type: Multicenter R-01
Title: Prospective investigation of pulmonary embolism DX-II (PIOPED II)
Role: Co- investigator (Local PI: Pam Woodard, MD, Dept. Radiology; National PI: Paul Stein, MD)

Ongoing Research Support - Private
1997 - 2001
Source: Mallinckrodt Medical
Type: Investigator initiated / pharmaceutical sponsored multicenter trial
Title: Cost-effectiveness of helical CT versus ventilation perfusion scintigraphy for evaluation of pulmonary embolism
Role: Investigator (PI: Pam Woodard, MD, Dept. Radiology)

2000-2002
Source: Organon, Inc.
Type: Industry sponsored multicenter trial
Title A multicentre, multinational, randomized, open-label study comparing the efficacy and safety of once daily Org31540/SR90107A versus adjusted-dose intravenous unfractionated heparin in the initial treatment of acute symptomatic pulmonary embolism; Study Number 63123
Role: Principal Investigator

2000-2002
Source: Sanofi-Synthelabo, Inc.
Type: Industry sponsored multicenter trial
Title: A multicentre, randomized, double-blinded study comparing the efficacy and safety of once daily Org31540/SR90107A versus twice daily enoxaparin in the initial treatment of acute symptomatic deep vein thrombosis; Protocol Number ECF 2441
Role: Principal Investigator

2000-2002
Source: Intermune Pharmaceuticals, Inc.
Type: Industry sponsored multicenter trial
Title: A randomized, double-blind, placebo-controlled, Phase III study of the safety and efficacy of subecutaneous recombinant interferon gamma-1b (IFN-gamma 1b) in patients with idiopathic pulmonary fibrosis; Protocol Number GIPF-001
Role: Investigator (PI: John Lynch, MD, Dept. Medicine)

Completed Research Support - Government
11/1/98 - 6/31/99
Source: Agency for Health Care Policy and Research; F32 HS00124-02
Type: Individual National Research Service Award (Renewal)
Title: Quality of life in patients with emphysema
Role: Principal Investigator

11/1/97 - 10/31/98
Source: Agency for Health Care Policy and Research; F32 HS00124-01
Type: Individual National Research Service Award
Title: Quality of life in patients with emphysema
Role: Principal Investigator

1997 - 1998
Source: National Institutes of Health; National Heart, Lung and Blood Institute; HR-97-02
Type: Request for proposals
Title: Lung volume reduction surgery for emphysema: a multi-center assessment and prospective registry (National Emphysema Treatment Trial)
Role: Investigator (PI: Joel D. Cooper, MD, Dept. Surgery)

6/16/96-6/15/97
Source: National Institutes of Health; National Heart, Lung and Blood Institute; HL 07317-18
Title: Institutional National Research Service Award
Role: Fellow Trainee (PI: Michael J. Holtzman, MD, Dept. Medicine)

Completed Research Support - Private
1995 - 1996
Source: Rhône-Poulenc Rorer Pharmaceuticals Inc.
Type: Industry sponsored multicenter trial
Title: A multicenter, randomized, partially-blind, parallel-group, clinical trial to compare the efficacy and safety of twice and once daily subcutaneously administered enoxaparin and continuous infusion heparin in the treatment of patients with deep venous thrombosis with or without pulmonary embolism; RP54563Q, protocol 529
Role: Principal Investigator

3/1/95 - 6/30/99
Source: Radiological Society of North America (RSNA) Research and Education Fund
Type: Seed grant research program
Title: Analysis of respiratory movements in patients with severe emphysema undergoing lung volume reduction surgery
Role: Collaborator (PI: David S. Gierada, MD, Dept. Radiology)

1995-1997
Source: Jewish Hospital Foundation Research Fund
Type: Foundation Grant
Title: Exercise response of patients before and after lung volume reduction surgery
Role: Investigator (PI: Mitchell Horowitz, MD and then Stephen S. Lefrak, MD, Dept. Medicine)

Division of Pulmonary and Critical Care Medicine
Department of Medicine
Washington University School of Medicine