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Daniel P. Schuster, M.D. Professor of Medicine and Radiology
CONTACT INFORMATION
Washington University School of Medicine EDUCATION/TRAINING
University of Michigan, B.A. 1972 Zoology POSITIONS
Instructor in Medicine, 1981-1982, Washington University School of Medicine HONORS
Established Investigator, American Heart Association, 1987-1992 PUBLICATIONS Mitchell JP, Schuller D, Calandrino FS, Schuster DP: Improved outcome based on fluid management in critically ill patients requiring pulmonary artery catheterization. Amer Rev Respir Dis 1992; 145:990-998. Kaplan JD, Calandrino FS, Schuster DP: Effects of smoking on pulmonary vascular permeability. Amer Rev Respir Dis 1992; 145:712-715. Kaplan JD, Trulock EP, Cooper JD, Schuster DP: Pulmonary vascular permeability after lung transplantation: A positron emission tomographic study. Amer Rev Respir Dis 1992; 145:954-957. Kaplan JD, Trulock EP, Anderson DJ, Schuster DP: Pulmonary vascular permeability in interstitial lung disease: A positron emission tomographic study. Amer Rev Respir Dis 1992; 145:1495-1498. Schuster DP, Sandiford P, Stephenson A. Thromboxane receptor stimulation/inhibition and perfusion redistribution after acute lung injujry. J Appl Physiol 1993; 75:2069-2078. Hamvas A, Schuster DP. Bronchial and reverse pulmonary venous blood flow protect the lung from ischemia-reperfsuion injury. J Appl Physiol 1994; 77:731-736. Sandiford P, Province M, Schuster DP. Distribution of regional density and vascular permeability in the adult respiratory distress syndrome. Am J Respir Crit Care Med 1995; 151:737-742. Markham J, McCarthy TJ, Welch MJ, Schuster DP. In vivo measurements of pulmonary angiotensin converting enzyme kinetics. I. Theory and error analysis. J Appl Physiol 1995; 78(3):1158-1168. Schuster DP, McCarthy TJ, Welch MJ, Holmberg S, Sandiford P, Markham J. In vivo measurements of pulmonary angiotensin converting enzyme kinetics. II. Implementation and application. J Appl Physiol 1995; 78(3):1169-1178. Schuster DP, Kaplan JD, Welch MJ, Markham J. Measurements of regional pulmonary blood flow in humans with PET. J Nucl Med 1995; 36:371-377. Schuster DP, AH Stephenson, S.Holmberg, P. Sandiford. Effect of eicosanoid inhibition on the development of pulmonary edema after acute lung injury. J Appl Physiol 1996; 80:915-923 Schuster DP, EC Crouch, WC Parks, T Johnson, MD Botney. Angiotensin converting enzyme expression in primary pulmonary hypertension. Am J Respir Crit Care Med, 1996; 154: 1087-1091 McCarthy TJ, Dence C, Holmberg S, Markham J, Schuster DP, Welch MJ. Inhaled [13N] nitric oxide: a positron emission tomography (PET) study. Nucl Med Biol 1996; 23:773-777. Tanaka Y, Schuster DP, Davis EC, Patterson GA, Botney MD. The role of vascular injury and hemodynamics in rat pulmonary artery remodeling. J. Clin. Invest. 1996;98:434-442. Okada K, Bernstein ML, Zhang W, Schuster DP, Botney MD. Angiotensin converting enzyme inhibition delays pulmonary vascular neointimal formation. Am J Respir Crit Care Med 1998; 158:939-950. Schuster DP, Markham J, Welch, MJ. PET measurements of pulmonary vascular permeability with Ga-68 Transferrin or C-11 methylalbumin. Crit Care Med 1998;26:518-524. Gust R, Kozlowski J, Stephenson AH, Schuster DP. Synergistic hemodynamic effects of low-dose endotoxin and acute lung injury. Am J Respir Crit Care Med 1998;157:1919-1926. Gust R, McCarthy TJ, Kozlowski J, Stephenson AH, Schuster DP. Response to inhaled nitric oxide in acute lung injury depends on distribution of pulmonary blood flow prior to its administration. Am J Respir Crit Care Med 1999;159:563-570 Gust R, Kozlowski J, Stephenson AH, Schuster DP. Role of cyclooxygenase-2 in oleic acid-induced acute lung injury. Am J Respir Crit Care Med 1999; 160:1165-1170 Qing F, McCarthy TJ, Markham J, Schuster DP. Pulmonary angiotensin converting enzyme (ACE) binding and inhibition in humans: a positron emission tomography study. Am J Respir Crit Care Med 2000; 161: 2019-202. Gust R, Schuster DP. Vascular remodeling in experimentally-induced subacute canine pulmonary hypertension. Exp Lung Res 27: 1-12, 2001 Schuster DP, JK Kozlowski, TJ McCarthy, J Morrow, A Stephenson. Effect of endotoxin on oleic acid lung injury does not depend on priming. J Appl Physiol 2001; 91:2047-2054. Brimioulle S, Julien V, Gust R, Kozlowski JK, Naeije R, Schuster DP. Importance of hypoxic vasoconstriction in maintaining oxygenation during acute lung injury. Crit Care Med 2002; 30:874-880. Schuster DP, JK Kozlowski, TJ McCarthy, J Morrow, A Stephenson. Effect of endotoxin on oleic acid lung injury does not depend on priming. J Appl Physiol 2001; 91:2047-2054. Schuster DP, C Anderson, J Kozlowski, N Lange. Regional pulmonary perfusion in patients with pulmonary edema. J Nucl Med 2002; 43: 863-870. Abraham E, C Naum, V Bandi, et al. Efficacy and safety of LY315920, a selective inhibitor of 14-kDa Type IIa PLA2, in patients with suspected sepsis and organ failure. Crit Care Med (in press). Schuster DP, T Stark, J Stephenson, H Royal. Detecting lung injury in patients with pulmonary edema. Intens Care Med 2002; 28: 1246-1253. Schuster DP, J Kozlowski, L Hogue, TW Ferkol. Imaging lung inflammation in a murine model of Pseudomonas infection: a positron emission tomography study. Exp Lung Res; 2003; 29: 45-57 Schuster DP, Metzler M, Opal S, Lowry S, Balk R, Abraham E, Levy H, Slotman G, Coyne E, Souza S, Pribble J, and the Pafase ARDS Prevention Study Group. Recombinant platelet-activating factor acetylhydrolase to prevent acute respiratory distress syndrome and mortality in severe sepsis: A Phase IIb, multicenter, randomized, placebo-controlled, clinical trial. Crit Care Med 2003; 31: 1612 Richard J-C., Z. Zhou, D. E. Ponde, C. S. Dence, P. Factor, P. N. Reynolds, G. D. Luker, V. Sharma, T. Ferkol, D. Piwnica-Worms, D. P. Schuster. Imaging Pulmonary Gene Expression With Positron Emission Tomography (PET). Am J Respir Crit Care Med 2003; 167: 1257-1263 Richard J-C, Factor P, Welch L, Schuster DP. Imaging the spatial distribution of transgene expression in the lungs with positron emission tomography. Gene Therapy, 2003; in press. RESEARCH SUPPORT
Ongoing Research Support R01 HL32815 3/1/00-2/28/04 (Schuster) 3/01/02-2/28/05
Division of Pulmonary and Critical Care Medicine
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