Marin H. Kollef, M.D., FACP, FCCP

Professor of Medicine

CONTACT INFORMATION

Washington University School of Medicine
660 S. Euclid Avenue, Campus Box 8052
St. Louis, MO 63110
(314) 454-8764

EDUCATION/TRAINING

Under-Graduate Education:
U.S. Military Academy, West Point, NY; Bachelor of Science, 1975-1979
Graduate Education:
University of Rochester School of Medicine and Dentistry, Rochester, NY; Doctor of Medicine, 1979-1983
Internship and Residency (Internal Medicine):
Madigan Army Medical Center, Tacoma, WA; 1983-1986 (John Redmond, M.D., Director)
Fellowship (Pulmonary Disease and Critical Care):
Madigan Army Medical Center, Tacoma, WA; 1986-1988 (Hal Cragun, M.D., Director)
Fred Hutchinson Cancer Institute, Seattle, WA; Bone Marrow Transplant Critical Care Service, 1 February 1988-30 March 1988 (Joan Clark, M.D., Director)

POSITIONS

Academic Positions/Employment:
Washington University School of Medicine
Professor of Medicine 2005-present
Associate Professor of Medicine 1998-2004
Assistant Professor of Medicine 1992-1997
Acting Director, Critical Care Program, Dept. Of Medicine, 1994-1995

Hospital Appointments: Director, Medical Intensive Care Unit, Fitzsimons Army Medical Center, Aurora, CO, 1988?1992
Staff Physician: Barnes-Jewish Hospital, St. Louis, MO, 1992-present
Assistant Director, Medical Intensive Care Unit, Barnes-Jewish Hospital, 1992-1995
Director, Medical Intensive Care Unit, Barnes-Jewish Hospital, 1995-present
Director, Respiratory Care Services, Barnes-Jewish Hospital, 1994-present

Hospital/University Committees: BJH Critical Care Committee, 1992-present (Chairman 1994-1995, 1999-2000)
BJC Critical Care Performance Improvement Committee, 1996 - present
BJH Physician Advisory Committee, 1996-1997

Military Service: (Continuing military obligation: none) United States Military Academy, West Point, New York; Cadet: 1975-1979
Madigan Army Medical Center, Tacoma, Washington; Captain: 1983-1988
Fitzsimons Army Medical Center, Aurora, Colorado; Captain/Major: 1988-1990
First Infantry Division (Mechanized), Operations Desert Shield/ Desert Storm; Medical
Treatment Platoon Leader (Saudi Arabia, Kuwait, Iraq): November 1990-May 1991
Fitzsimons Army Medical Center, Aurora, Colorado; Major: May 1991-1992

OTHER EXPERIENCE AND PROFESSIONAL MEMBERSHIPS

The Honor Society of Phi Kappa Phi, 1980 to present
American College of Physicians, 1983 to present (Fellowship granted May 1991)
American College of Chest Physicians, 1986 to present (Fellowship granted October 1990)
American Thoracic Society, 1988 to present
Society of Critical Care Medicine, 1991 to present
American Association for Respiratory Care, 1994 to present
American Society of Clinical Investigation, 2000 to present
Alpha Omega Alpha, 2001 to present

ACADEMIC HONORS

Academic
First Place Winner of Associate's Presentation Award, American College of Physicians
(State Regional meeting), Tacoma, WA; September 1987
First Place Winner of Associate's Presentation Award, XVI World Congress on Diseases of the Chest and the 55th annual Scientific Assembly, American College of Chest Physicians, Boston, MA; October 1989
Outstanding Graduating Medical Resident, 1986, Madigan Army Medical Center, Tacoma, Washington
Outstanding Teacher of the Year Award; 1988-1989; Fitzsimons Army Medical Center, Aurora, Colorado
Attending Physician of the Year Award; 1988-1989; Department of Medicine, Fitzsimons
Army Medical Center, Aurora, Colorado
Outstanding Teacher of the Year Award; 1989-1990; Fitzsimons Army Medical Center, Aurora, Colorado
Attending Physician of the Year Award; 1989-1990; Department of Medicine, Fitzsimons Army Medical Center, Aurora, Colorado
Outstanding Teacher of the Year Award; 1990-1991; Fitzsimons Army Medical Center, Aurora, Colorado
Outstanding Teacher of the Year Award; 1993-1994; Department of Medicine, Washington University School of Medicine, St. Louis, MO
Outstanding Teacher of the Year Award; 1995-1996; Department of Medicine, Washington University School of Medicine, St. Louis, MO
Selected to "Best Doctors in America", Central Region: 1996-present
Quality Leadership Award, 1997, BJC Health System, Respiratory Care Services
The John P. Atkinson Outstanding Teacher Award; 1998-1999; Department of Medicine, Washington University School of Medicine, St. Louis, MO
Chest Foundation, Young Investigator Award 1999
Alfred Soffer Research Award, American College of Chest Physicians 2000
Elected to Alpha Omega Alpha Honor Medical Society 2001
Team Award for Quality Improvement 2001; Barnes-Jewish Hospital "VAP Prevention Program"

Military Army Service Ribbon
Army Commendation Medal (For Teaching Achievement 1990)
Army Achievement Medal (For Teaching Achievement 1991)
Bronze Star (For services rendered during Operation Desert Storm)
National Defense Service Medal (Operation Desert Storm)
Southwest Asia Medal (Operation Desert Storm)
Liberation of Kuwait Medal (From Saudi Arabian Government)
United Nations Service Medal
Meritorious Unit Citation
[701st MSB, First Infantry Division (Mechanized), Operation Desert Storm]
Meritorious Service Metal
Combat Medical Badge in support of Combat Operations [First Infantry Division (Mechanized), Operation Desert Storm]
Army Parachutist Wings

PUBLICATIONS

Kollef MH. Outcome prediction in the intensive care unit. In: The Transition from Cure to Comfort: Managing Death in the Intensive Care Unit. Curtis JR, Rubenfeld GD (eds). Oxford University Press 2000:39-57.

Kollef MH. Outcomes research at the end of life. Crit Care Med 2000; 28:269-270.

Kollef MH. The nonpharmacologic prevention of ventilator-associated pneumonia. In: 1999 Yearbook of Intensive Care and Emergency Medicine. Vincent JL (ed). Springer-Verlag, Berlin, 2000; 123-134.

Kollef MH. A pet fancier's severe respiratory distress. Cortlandt Forum 2000; 13:176-180.

Kollef MH. Selective digestive decontamination (SDD) - con view point. Crit Care and Crit Care Forum (http://ccforum.com) 2000; 4:327-332.

Kollef MH. Ventilator-associated pneumonia: the importance of initial empiric antibiotic selection. Infect in Med 2000; 17:265-283.

Kollef MH. The importance of adequate antimicrobial treatment for nosocomial pneumonia. Mediguide to Pulmonary Medicine 2000; 7:1-6.

Kollef MH. Inadequate antimicrobial treatment: An important determinant of outcome for hospitalized patients. Clin Infect Dis 2000; 31 (Suppl 4):S131-S138.

Kollef MH. Improving clinical outcomes: Sometimes more is better! Lancet 2000; 356 (9234):956-957.

Kollef MH. Medical trainee experience versus optimizing clinical outcomes: Achieving the best of both. Respir Care 2000; 45:938-939.

Kollef MH. Antimicrobial heterogeneity: Can it help to prevent resistance? Pulmonary Perspectives 2000; 17:1-4.

Kollef MH. Anaerobic bacteria are important in ventilator-associated pneumonia (VAP): Con view. Pulmonary Infections Forum 2000; IV:3-6.

Kollef MH. Pulmonary Embolism. In: Pulmonary Board Review 2000. American College of Chest Physicians. Northbrook, IL 2000:425-436.

Kollef MH. Hypoxic Respiratory Failure. In: Pulmonary Board Review 2000. American College of Chest Physician. Northbrook, IL 2000:517-528.

Kollef MH. Critical Care. In: Manual of Medical Therapeutics. 30th Edition. Little, Brown and Company. Boston 2001; 195-215.

Kollef MH. Mechanical ventilation: Protocol driven strategies. In: Ventilator Management Strategies for Critical Care. Hill NS, Levy M (eds). Marcel Dekker, Inc. 2001; 158:111-136.

Kollef MH. Is there a role for antibiotic cycling in the intensive care unit? Crit Care Med 2001; 29 (Suppl 4):N135-N142.

Kollef MH. The intensive care unit in antimicrobial resistance. Hospital Practice 2001:60-69.

Iregui M, Kollef MH. Ventilator-associated pneumonia and the acute respiratory distress syndrome. Semin Respir Crit Care Med 2001; 22:317-325.

Kollef MH. What's new in ventilator-associated pneumonia. Anesthesiology 2001; 94:551-553.

Kollef MH. Antibiotic resistance among gram-positive bacteria in the hospital setting: what can we do about it? Medscape Treatment Update: http://www.medscape.com/uptodate/2000/12.00/utd1201.14.koll/utd1201.14.koll-01.html.

Kollef MH. Hospital-acquired pneumonia and de-escalation of antimicrobial treatment. Crit Care Med 2001; 29:1473-1475.

Kollef MH, Niederman M. Antimicrobial resistance in the ICU: The time for action is now. Crit Care Med 2001; 29(Suppl 4):N63.

Kollef MH. Optimizing antibiotic therapy in the intensive care unit setting. Critical Care 2001; 5:189-195.

Chakinala M, Trulock E, Kollef MH. Critical care of lung transplant recipients. J Intensive Care Med 2001 (In Press).

Kollef MH. Is prevention of ventilator-associated pneumonia cost effective: A North American View. In: Infection Control in the ICU Environment. Bonten M, Weinstein RA (eds). Kluwer Academic Publishers 2002; 141-154.

Ibrahim E, Kollef MH. The use of protocols to improve clinical outcomes in acute respiratory failure. Crit Care Clin 2001; 17: 989-1001.

Kollef MH. Selective digestive decontamination (SDD) should not be routinely employed. Chest 2003; 123:464s-468s.

Iregui M, Kollef MH. Prevention of ventilator-associated pneumonia: Selecting interventions, which make a difference Chest 2002; 121:679-681.

Kollef MH. Strategies in the prevention of ventilator-associated pneumonia In: Critical Care Infectious Diseases. Rello J, Valles J, Kollef M (eds). Kluwer Academic Publishers 2001; 707-718.

Kollef MH. Intensive care units and the development of resistance to antimicrobial agents. In: Infeccion 2002. Bouza E, Picato JJ (eds). Fundacion para el Estudio de la Infeccion 2002; 267-292.

Ely EW, Meade MO, Haponik EF, Kollef MH, Cook DJ, Guyatt GH, Stoller JK. Mechanical ventilation weaning protocols driven by nonphysician health-care professional: evidence-based clinical practice guidelines. Chest 2001; 120: 454S-463S.

Kollef MH. Prevention of ventilator-associated pneumonia. In: Perspectives in Critical Care Infectious Disease (Volume 4: Ventilator-Associated Pneumonia). Wunderink RG, Rello J (eds). Kluwer Academic Publishers 2001; 45-60.

Iregui M, Kollef MH. Non-pharmacologic prevention of hospital-acquired pneumonia. Semin Respir Crit Care Med 2002; 23: 489-496.

Kollef MH. Prevention of antibiotic resistance. (Letter) Ann Intern Med 2002; 136: 173.

Shorr A, Kollef MH. The quick and the dead: The evaluation of pulmonary infiltrates in immunocompromised hosts. Chest 2002; 122: 9-12.

lef MH. Critical care in: Manual of Medical Therapeutics. 31st Edition. Little Brown and Company. Boston 2003; (In Press).

lef MH. Appropriate antibiotic therapy for VAP and sepsis: A necessity not an issue for debate. Intensive Care Med (In Press).

lef MH. The diagnosis and medical management of ventilator-associated pneumonia (Monograph) (In Press).

Kollef MH. Impact of inappropriate antimicrobial selection on outcome. In: Guidelines and Formulary Considerations in Infectious Disease. Owens, Ambrose, Nightingale (eds). Marcel Dekker, Inc. (In Press).

Kollef MH. Lectures in hospital infections. Part one: Nosocomial pneumonia. Science Press Ltd. (In Press).

Kollef MH. Appropriate empirical antibacterial therapy for nosocomial infections. Drugs (In Press).

Kollef MH. An Empirical approach to treatment of multidrug-resistant ventilator-associated pneumonia. Clin Infect Dis 2003; 36:1119-1121.

Warren DK, Kollef MH. Infection control and surveillance in the intensive care unit. In: Principles of Critical Care. Hall JB, Schmidt G, Wood L (eds). McGraw Hill Publishers (In Press).

RESEARCH SUPPORT

Bard Medical Inc. Preventing VAP with a silver-coated endotracheal tube, (Principal Investigator) 2002-2003

Agency for Healthcare Research and Quality. Surveillance analysis and interventions to improve patient safety. 2002-2004

Department of Veteran Affairs. Intensive vs. conventional renal support in acute renal failure (Co-Principal Investigator) 2003-2005

Intrabiotics Pharmaceuticals, Inc. VAP prevention with iseganan (Principal Investigator) 2003-2004

Division of Pulmonary and Critical Care Medicine
Department of Medicine
Washington University School of Medicine