Robert H. Arch, Ph.D.

Assistant Professor of Medicine
Assistant Professor of Pathology and Immunology

EDUCATION/TRAINING

University of Würzburg, Germany, MA 1990 Biology
University of Würzburg, Germany, PhD 1994 Immunology/Cell Biology

POSITIONS

10/94 - 09/95 Postdoctoral position, Department of Immune Regulation and Tumor Defense at the German Cancer Research Center, Heidelberg, Germany; Head of the Department, Margot Zöller, M.D.
02/96 - 12/98 Postdoctoral position, Howard Hughes Medical Institute, University of Chicago, Gwen Knapp Center for Lupus and Immunology Research, Chicago, IL. Head of the Department, Craig Thompson, M.D.
01/99 - 07/99 Research Associate, Department of Medicine, University of Chicago, Gwen Knapp Center for Lupus and Immunology Research, Chicago, IL. Head of the Department, Craig Thompson, M.D.
08/99 - 07/00 Research Instructor, Department of Internal Medicine, Pulmonary and Critical Care Medicine, Washington University School of Medicine, St. Louis, MO.
07/00 - present Assistant Professor of Medicine, Assistant Professor of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO.

PUBLICATIONS

RESEARCH SUPPORT

ONGOING

1 RO1 HL67312-01 (PI Arch, Robert) 05/15/01 - 04/30/06
NIH/NHLBI
"CD30-A Molecular Switch for Lymphocyte Apoptosis"
The goal of this proposal is to identify and characterize novel costimulatory pathways of T cells that play a role in inflammatory lung disease.
Role: PI

NIH 5 P60 DK20579 (PI Arch, Robert) 12/01/01 - 11/30/03
Washington University DRTC
"CD30-induced signaling events in autoimmune diabetes"
The goal of this proposal is to characterize signaling complexes induced by CD30 in diabetogenic T cells.
Role: PI

Cancer Research Institute 07/01/02 - 06/30/06
"TRAF-mediated signaling pathways regulating tumor cell apoptosis"
The goal of this proposal is to define TRAF-mediated signal transduction pathways in hematopoietic tumor cells and to develop novel therapeutic approaches.
Role: PI

5 P50 HL56419-07 09/01/01 - 08/31/06
"Mechanisms of airway inflammation and remodeling Project 1: Immune cell development: Th1 vs Th2 pathways"
The goal of this proposal is to compare the role of TNFR-related molecules in Th1 and Th2 cells.
Role: Co-Investigator (PI Kenneth Murphy)

Overlap: None

PENDING

RO1 (PI Arch, Robert) 05/01/04 - 04/30/09
NIH/NHLBI
"TRAF2-mediated redox signaling"
The goal of this proposal is to define the role of TRAF2 in regulating the cellular redox potential.
Role: PI Ê

Overlap: None

Division of Pulmonary and Critical Care Medicine
Department of Medicine
Washington University School of Medicine