Mouse Smoking Model Unit
Mouse Smoking Model Unit
Affiliated Department/Program(s): Internal Medicine, Pulmonary Biology
Faculty Supervisor: Yong Zhang yzhang@dom.wustl.edu 747-0953
Supervisor: Dale Kobayashi dkobayas@dom.wustl.edu 454-5618
The Mouse-Smoking Core in the Pulmonary and Critical Care Medicine Division has been in service for over 15 years. It is supported mainly by NHLBI/NIH. Using 10 cigarette-smoking machines, each with compartments for 5 mice, we can expose over 400 mice/day, 6 days per week. We can administer drugs to mice through oral gavage, aerosolization, IP injection, and by food or water. We have worked with many Departments/Divisions within Washington University, including Cardiovascular Surgery, Orthopedics, Physiology and Cell & Molecular Biology, Dermatology, and Hematology/Oncology. Publications in high impact journals (e.g. Science, Journal of Clinical Investigation, Am. J. Path,) have resulted from mice smoked by the Core.
If interested in using this service please contact the Supervisor. Fees for service will depend on the length of experiment, number of mice, and type of drug administration.
Department of Medicine
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