Biographical Sketch

Research

I am interested in diagnosis and consequences of respiratory virus infection. We have been studying epidemiology/impact of newly discovered respiratory virus infection and its relation to asthma, new diagnostic methods for respiratory virus infection in severe respiratory illness, association of asthma and antiviral response in urban birth cohort.<.p>

I am also interested in clinical trials in asthma. I have been involved in clinical studies in asthma at Asthma and Airway Translational Research Unit.

Publications

1. Sumino K, Okuda K, Okubo T; The Adjuvant Effect of QS-21 on HIV-1-specific Immune Responses Induced by DNA Vaccination. Yokohama Medical Journal 1998; 49:351-358.

2. Kusakabe K, Xin, K, Katoh, H, Sumino K, Hagiwara E, Kawamoto S, Okuda K, Miyagi Y, Aoki I, Nishioka K, Klinman D, Okuda K; The timing of GM-CSF expression plasmid administration influences the Th1/Th2 response induced by HIV-1 specific DNA vaccine. J Immunol, 2000; 164:3102-3111

3. Sumino KC, Agapov E, Trulock EP, Pierce RA, Trulock EP, Pfeifer JD, Ritter JH, Gaudreault-Keener M, Storch GA, Holtzman MJ. Detection of severe human metapneumovirus infection by real-time polymerase chain reaction and Histological assessment. J Infect Dis. 2005; 192(6):1052-1060.

4. Agapov E, Sumino KC, Gaudreault-Keener M, Storch GA, Holtzman MJ. Genetic variability of human metapneumovirus infection: evidence of a shift in hMPV genotype without a change in illness. J Infect Dis. 2005; 193(3):396-403

Book Chapters/Reviews

1. Holtzman, M. J., Tyner, J. W., Kim, E. Y., Patel, A. C., Grayson, M. H., Shornick, L. P., Sumino, K. C., Agapov, E., and Zhang, Y. Acute and chronic airway responses to viral infection: implications for asthma and chronic bronchitis/COPD. Proc. Am. Thorac. Soc. 2:132-140, 2005.

2. Holtzman MJ, Kim EY, Lo MS, Tyner JW, Shornick LP, Sumino KC, Zhang Y. Defining and adjusting divergent host responses to viral infection. Immunol Res. 2005; 32(1-3):123-41.