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John P. Lynch, M.D.
John P. Lynch, M.D.

John P. Lynch, M.D.

Professor of Medicine
Pulmonary & Critical Care Medicine

Washington University School of Medicine
660 S. Euclid Avenue, Campus Box 8052
St. Louis, MO 63110
(314) 747-1617 (phone)
(314) 362-8015 (fax)

jlynch@dom.wustl.edu

Research Interests

Biographical Sketch

Research

My research interests are focused on the clinical aspects of the management of lung transplant patients. Specifically, we are studying health related quality of life in lung transplant recipients. We are also involved with multi-center trials that are aimed at improving immunosuppression protocols as well as testing novel interventions that are designed to reduce the incidence of reperfusion injury in the lung allograft.

Publications

1. Paranjothi S, Yusen RD, Kraus MD, Lynch JP, Patterson GA, Trulock EP. Lymphoproliferative disease after lung transplantation: Comparison of presentation and outcome of early and late cases. J Heart Lung Transplant 2001; 20:1054-1063

2. Sanchez JL, Kruger RM, Paranjothi S, Trulock EP, Lynch JP, Hicks C, Shannon WD, Storch GA. Relationship of cytomegalovirus viral load in blood to pneumonitis in lung transplant recipients. Transplantation 2001; 72:733-735

3. Rizzo M, SivaSai KS, Smith MA, Trulock EP, Lynch JP, Patterson GA, Mohanakumar T. Increased expression of inflammatory cytokines and adhesion molecules by alveolar macrophages of human lung allograft recipients with acute rejection: Decline with resolution of rejection. J Heart Lung Transplant 2000; 19:858-865

4. Meyers BF, Lynch JP, Battafarano RJ, Guthrie TJ, Trulock EP, Cooper JD, Patterson GA. Lung transplantation is warranted for stable, ventilator-dependent recipients. Ann Thorac Surg 2000; 70:1675-1678

5. Lynch JP, Forman SA, Graff SI, Gunby MC. High-risk population health management – achieving improved patient outcomes and near-term financial results. The American J Managed Care 2000; 6(7):781-791, 31-41

6. Vizza CD, Yusen RD, Lynch JP, Fedele F, Patterson GA, Trulock EP. Outcome of patients with cystic fibrosis awaiting lung transplantation. 2000, In Press

7. Meyers BF, Lynch JP, Trulock EP, Guthrie T, Cooper JD, Patterson GA. Single versus bilateral lung transplantation for idiopathic pulmonary fibrosis: A ten-year institutional experience. J Thorac Cardiovasc Surg 2000; 120:99-107

8. SivaSai KSR, Smith MA, Poindexter NJ, Sundaresan SR, Trulock EP, Lynch JP, Cooper JD, Patterson GA, Mohanakumar T. Indirect recognition of donor HLA class I peptides in lung transplant recipients with bronchiolitis obliterans dyndrome. Transplantation 1999; 67:1094-1094

9. Jaramillo A, Smith MA, Phelan D, Sundaresan S, Trulock EP, Lynch JP, Cooper JD, Patterson GA, Mohankumar T. Development of Eliza-detected anti-HLA antibodies precedes the development of bronchiolitis obliterans syndrome and correlates with progressive decline in pulmonary function after lung transplantation. Transplantation 1999; 67:1155-1161

10. Kruger RM, Shannon WD, Arens MQ, Lynch JP, Storch GA, Trulock EP. The impact of Gancyclovir-resistant cytomegalovirus infection after lung transplantation. Transplantation 1999; Vol 68:1272-1279, No. 9

11. Meyers BF, Lynch JP, Trulock EP, Guthrie TJ, Cooper JD, Patterson GA. Lung transplantation: A decade of experience. Annals of Surgery 1999; 230:362-371

12. Calhoun R, SivaSai KSR, Sundaresan S, Trulock EP, Lynch JP, Patterson GA, Cooper JD, Mohanakumar T. Development of bronchiolitis obliterans syndrome despite blood chimerism in human lung transplant recipients. Transpl Int 1999; 12:439-446

Book Chapters/Reviews

Lynch JP, Trulock EP, Cooper JD. The perioperative care of lung transplant recipients. Eds. Bone RC, Dantzker DR, George RB, Matthay RA, Reynolds HY. Pulmonary and Critical Care Medicine. Chicago: Mosby-Year Book, Inc, 1998