Biographical Sketch

Research

1) Validation of new non-invasive hemodynamic technology by transcutaneous Doppler based technology

2) Validation of new markers for determining preload responsiveness

3) PiCCO guided hemodynamic optimization versus early goal directed therapy for septic shock

Publications

1. Micek ST, Isakow W, Shannon W, Kollef MH. Predictors of hospital mortality for patients with severe sepsis treated with Drotrecogin alfa (activated) Pharmacotherapy 2005 Jan; 25(1):26-34.

2. Isakow W, Kollef MH. Preventing ventilator- associated pneumonia. An evidence-based approach of modifiable risk factors. Seminars in Respiratory and Critical Care Medicine 2006 Feb; 27(1):5-17

3. Jeffres MN, Isakow W, Doherty JA, et al. Predictors of mortality for Methicillin-Resistant Staphylococcus aureus Health-Care-Associated Pneumonia: specific evaluation of Vancomycin pharmacokinetic Indices. Chest 2006; 130: 947-955

4. Isakow W, Schuster DP. Extravascular lung water measurements and hemodynamic monitoring in the critically ill: bed-side alternatives to the pulmonary artery catheter. Am J Physiol Lung Cell Mol Physiol 2006: 291: L1118- L1131

5. Isakow W, Morrow LE, Kollef MH. Probiotics for Preventing and Treating Nosocomial Infections: Review of Current Evidence and Recommendations. Chest 2007, 132(1): 286-294

6. Jeffres MN, Isakow W, Doherty JA, Micek ST, Kollef MH. A retrospective analysis of possible renal toxicity associated with vancomycin in patients with health care-associated methicillin-resistant Staphylococcus aureus pneumonia. Clin Ther. 2007 Jun;29(6):1107-15.

Book Chapters/Reviews

1. Co-editor: The Washington Manual of Critical Care Medicine 2007. Kollef, Bedient, Isakow and Witt. Lippincott, Williams and Wilkins

2. Respiratory failure. In ACP Medicine 2007